1. **Changes in Urination**: Increased urination at night, decreased output, or foamy urine. 2. **Fatigue and Weakness**: Anemia caused by reduced kidney function can lead to fatigue. 3. **Swelling (Edema)**: Fluid retention causing swelling in legs, hands, face, and abdomen. 4. **Persistent Back Pain**: Pain below the ribcage or tenderness could signal kidney issues. 5,
**Unexplained Weight Loss or Loss of Appetite**: Buildup of waste can cause weight loss and loss of appetite. 6. **Nausea and Vomiting**: Waste accumulation in the blood can lead to nausea, especially after meals. 7. **Difficulty Sleeping**: Due to nighttime cramps, restless legs, and frequent urination. 8. **Metallic Taste in the Mouth**: A sign of uremia from waste buildup. 9. **Muscle Cramps and Twitching**: Caused by electrolyte imbalances. 10. **Itchy Skin**: Toxin buildup can cause generalized itching.
